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Drug of choice for induction of labour?
Oxytocin
Drug of choice for ectopic pregnancy?
Methotrexate
Drug of choice for hypothyroidism?
Levothyroxine
Drug of choice for erectile dysfunction?
Sildenafil
Drug of choice for type 1 diabetes mellitus?
Insulin
Drug of choice for osteoporosis?
Alendronate
Drug of choice for hypercalcemia of malignancy?
Bisphosphonate
Drug of choice for paroxysmal supraventricular tachycardia?
Intravenous Adenosine
Drug of choice for WPW syndrome? (WPW=Wolff Parkinson White Syndrome)
Oral Flecainide(class 1c drug-sodium channel blocker)
Treatment of choice for WPW syndrome?
Radiofrequency Ablation
Half-life of amiodarone?
Half-Life = 53 days!!
Mechanism of action of digoxin?
Sodium Potassium Pump(Na+K+ATPase) Block
Which ACE inhibitor first approved by the FDA?
Captopril
What is Aliskiren?
It is a direct renin inhibitor used in hypertensive patients.
HLA associated with myasthenia gravis?
HLA B8
Bleeding in pons causes?
Coma and pinpoint pupil
The most common cause of stroke in elderly people?
Thrombosis
Todd's paralysis is mostly seen after?
Grand mal epilepsy
Neck rigidity without fever seen in?
Subarachnoid haemorrhage
deficiency seen in cortex in Alzheimer's disease?
Acetylcholine
Shrinking lung syndrome is seen in?
Systemic Lupus Erythematosus (SLE)
Initial investigation of choice in case of deep vein thrombosis?
Duplex USG
Bilateral upper-limb pulseless disease known as?
Takasayu arteritis
type of breathing seen in metabolic alkalosis?
Cheyne stroke breathing
Granulomatous condition with hypercalcemia seen in?
Sarcoidosis
Definitive treatment of hypermagnesemia?
Haemodialysis
Hypokalemic metabolic acidosis with hypertension seen in?
Liddle's syndrome
Which virus cause orchitis?
Mumps
Drug used for giardiasis?
Metronidazole
Libman-sacks endocarditis seen in?
SLE
Most common benign tumor of the oesophagus?
Leiomyoma
Most common malignant tumor of the oesophagus?
Squamous cell carcinoma
Most important prognostic factor for oesophageal cancer is?
Depth of invasion
Genes associated with Crohn's disease?
NOD, ATG 16 L, and IRGM
The most common site for Crohn's disease?
- Ileum (Most common)
- Ileocecal Valve (2nd Most common)
- Caecum (3rd most common)
Total number of bones in adult human?
206
Total number of ribs?
24
Total number of bones in skull?
22
Total number of bones in neck?
8 (7 vertebra+hyoid)
Total number of bones in vertebral column?
33
Normal respiratory rate?
16-20 breaths/minutes
Normal heart rate?
60-100 beats/minutes
Normal blood pressure?
120/80 mmHg
Total cranial nerves?
12 pair (24)
What is average birth length?
50 cm
Most common cause of mental retardation?
Down Syndrome(Trisomy 21)
First reflex present in newborn?
Swallowing Reflex (Present From Womb)
In infant, pneumonia diagnose by?
Increased Respiratory Rate
Inheritance of G6PD deficiency?
Autosomal Recessive
What is pan T cell marker?
CD 3
What is pan B cell marker?
CD 19
Largest organ of body?
Skin
Trochlear nerve supplies which muscle?
Superior oblique muscle [Extraocular muscle]
In which stage, 90% of hair present?
Anagen
Sign which appear first during mysthenia gravis?
Ptosis
Most specific antibody in systemic lupus erythromatosus?
Anti Smith Antibody
Beck's triad seen in?
Cardiac tamponade
What is the length of inguinal canal?
4 cm
Which muscle supplied by abducent nerve?
Lateral Rectus
Tympanic membrane derive from?
All 3 germ layers
Who is the governor of cell cycle?
RB gene [Retinoblastoma Gene]
Mention 3 names of permanent cell
- Neurons
- Cardiac muscle
- skeletal muscle
What is hypertrophy?
Increase in cell size
Most common cause of cell injury?
Hypoxia
What is pyknosis?
Nuclear Shrinkage
Bioavailability Measure By?
Area Under Curve (AUC)
Loading dose (drug) depend on??
Volume of distribution (Vd)
Maintenance dose of drug depend on?
Clearance
Microsomal Metabolic Reaction For Drug Metabolism?
Glucuronide Conjugation
Nicotinic Cholinergic Receptor?
Ganglia& Adrenal Medulla
Name Of Honeymoon Muscle?
Sartorius
Name Of Anti Rape Muscle?
Gracilis
Nerve Involved in Fracture Neck Of Fibula?
Common Peroneal Nerve
Most common nerve involved in leprosy?
Ulnar Nerve
Name Of Climbing Muscle?
Lattismus Dorsi
Type of blister in pemphigus vulgaris?
Suprabasal
Can be responsible for bezold jarisch reflex
Serotonin
Other names for Parkinson's disease?
Paralysis agitans
Histone methylation makes DNA _____ ??
Inactive
If RB gene is hypophosphorylated than cell cycle will stop at _____ ??
G1 phase
Histone acetylation makes DNA _____ ?
Active
Albumin is _____ acute phase reactant?
Negative
RDW deal with _____ ?
Anisocytosis
Decrease glutathione activity seen in _____ ?
Riboflavin Deficiency
Pellagra due to _____ deficiency?
Niacin
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